Stockholm3 developer Henrik Grönberg named Cancer Researcher of the Year

January 11, 2022

Professor Henrik Grönberg is awarded the Swedish Cancer Foundation’s Cancer Researcher of the Year 2022 for his research that enables early detection of prostate cancer. Henrik Grönberg’s research has led to the test Stockholm3.

The Cancer Foundation’s research committee, chaired by former chairman of the Nobel Committee, Klas Kärre, gave the following justification:

“For world-leading research on prostate cancer. For methods of detecting prostate cancer at an early stage, but also to avoid unnecessary examinations, as well as to identify the patients who need to be treated immediately. All this contributes to more individualized treatment, increased chance of cure and high quality of life.”

“I am very happy and honored to get this award. Prostate cancer is the most common and deadliest form of cancer for men in Sweden. Unfortunately, 2,300 men in Sweden alone still die every year. We now have the tools to introduce general screening, which would significantly reduce mortality from the disease,” said Professor Grönberg.

“The award from the Swedish Cancer Foundation shows the great value that Stockholm3 adds through earlier detection of prostate cancer and by simultaneously reducing unnecessary treatments. This award follows last summer’s award for best abstract in oncology at the European Association of Urology. We are very proud of these national and international awards, which are also important milestones in our work to establish Stockholm3 globally and radically improve the precision in prostate cancer diagnostics,” said David Rosén, CEO of A3P Biomedical.

Henrik Grönberg is a professor of cancer epidemiology at Karolinska Institutet and a senior physician. Henrik is a co-founder of A3P Biomedical and a leading expert in prostate cancer. Since 2005, Henrik has been a professor at Karolinska Institutet, where he leads a research group with 35 researchers focused on prostate cancer. He is also responsible for the Prostate Cancer Center at Capio S:t Göran’s Hospital in Stockholm.

About A3P Biomedical

A3P Biomedical is a company that specializes in advanced prostate cancer diagnostics. A3P’s main product, Stockholm3, is a clinically and commercially validated blood test for early detection and risk stratification of aggressive prostate cancer. A3P Biomedical is headquartered in Stockholm, Sweden. For more information, please visit www.a3p.com 

About Stockholm3

Stockholm3 is a blood-based test, that runs a combination of protein biomarkers, genetic biomarkers and clinical information through an algorithm to find the probability of clinically significant cancer at biopsy.

Stockholm3 has been evaluated in clinical studies including more than 90,000 men. It is extensively tested in large population-based screening trials, as well as in real world clinical utility studies in primary care, as a reflex test to PSA at values 1.5-20 ng/ml.  Benefits include the ability to reduce unnecessary MRIs, benign and Grade Group 1 prostate biopsies for men with elevated PSA, while simultaneously improving detection of clinically significant cancers in men with low or normal PSA values.  Using Stockholm3 leads to a more accurate risk assessment than the current PSA standard. Stockholm3 detects 40-90% more men with aggressive prostate cancer and, at the same time, reduces over-detection by 40-50% compared to PSA.

Multiple Stockholm3 studies have been published in high-impact journals such as The Lancet Oncology, Journal of Clinical Oncology, and European Urology. The studies address both the specificity and sensitivity of Stockholm3 in multi-ethnic populations as well as health-economic benefits of implementing it in clinical care. For more information about our clinical studies please visit www.a3p.com.

About prostate cancer

Prostate cancer is the most common cancer in men. In 2020, the global incidence of new prostate cancer cases was 1.4 million, and prostate cancer specific mortality 370,000. Global prostate cancer incidence and mortality is expected to rise by 100% and 85% respectively by 2040, driven by an ageing population.

Press contact:
Cecilia Edström
cecilia.edstrom@a3p.com
+46 72 226 2328

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New analysis in European Urology finds Stockholm3 cost effective for population-based screening

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Fast track publication of the STHLM3 MRI trial in The Lancet Oncology